Members of the Huberman Laboratory at Roswell Park Cancer Institute

Current Laboratory Members

Recent Past Laboratory Members

Recent laboratory pictures


Joel A. Huberman, Ph.D.
Professor of Cellular and Molecular Biology
Department of Cancer Genetics
Roswell Park Cancer Institute
Buffalo, New York 14263
716-845-3047 Office phone
716-845-8126 FAX
huberman@buffalo.edu

Joel provides overall direction to the laboratory and specific guidance for each of the research projects. In addition, he writes the grant applications that keep us funded, plays a strong role in writing each of the papers that emerges from the laboratory, and maintains the laboratory's computer network. Joel wishes to acknowledge the inspiration he receives from the other members of the laboratory and also from his colleagues Terry Beerman, Bill Burhans, David Kowalski and John Yates.
Here are some links to other Web resources developed by Joel:


Amna Chaudari, B.S.
Graduate Student
Department of Cancer Genetics
Roswell Park Cancer Institute
Buffalo, New York 14263
716-845-4404 Office phone
716-845-8126 FAX
amna666@yahoo.com amna.chaudari@roswellpark.org

Amna is cloning and characterizing replication origins from fission yeast telomeres, with a view to identifying the cis- and trans-acting factors that make them replicate in very late S phase.

Francois Faure, M.S.
Volunteer
Department of Cancer Genetics
Roswell Park Cancer Institute
Buffalo, New York 14263
716-845-1372 Office phone
716-845-8126 FAX
francois.faure@roswellpark.org

Francois is working with Bob Givens to purify and characterize early- and late-replicating minichromosomes from fission yeast.

Robert Givens, Ph.D.
Research Associate
Department of Cancer Genetics
Roswell Park Cancer Institute
Buffalo, NY 14263
716-845-1372 Office phone
716-845-8126 FAX
robert.givens@roswellpark.org

Bob is studying the effects of altered replication timing on chromatin structure in fission yeast. He is also attempting to purify early- and late-replicating plasmid minichromosomes from fission yeast cells, in the hope of identifying protein differences between these minichromosomes. He is also studying the structural properties of individual and clustered "Late Consensus Sequence (LCS)" elements (see Yompakdee & Huberman, 2004)

Gerald Jahreis
Technician
Department of Cancer Genetics
Roswell Park Cancer Institute
Buffalo, NY 14263
716-845-4404 Office phone
716-845-8126 FAX
gerald.jahreis@roswellpark.org

Gerry is our general and radiation safety officer. His responsibilities include keeping our large collection of strains and plasmids well organized, accessible and viable. In addition he assists other lab members with large research projects. He is becoming an expert in 2D gel electrophoresis.

Sanjay Kumar, M.S.
Graduate Student
Department of Cancer Genetics
Roswell Park Cancer Institute
Buffalo, New York 14263
716-845-4404 Office phone
716-845-8126 FAX
sanjay.kumar@roswellpark.org

Sanjay has recently demonstrated that the major pathway downstream of Cds1 in the fission yeast intra-S-phase checkpoint is the Cdc25-Cdc2 pathway. Thus the major reason for the slowing of S phase after DNA damage by MMS in fission yeast is inhibition of the Cdc2 cell cycle kinase. Whether Cdc2 kinase primarily regulates origin firing or fork movement is still unclear. Therefore, Sanjay is now using 2D gel electrophoresis to distinguish between these possibilities.

Anita Paul, MD
Volunteer
Department of Cancer Genetics
Roswell Park Cancer Institute
Buffalo, New York 14263
716-845-4404 Office phone
716-845-8126 FAX
paulanita@buffalo.com

Anita is assisting Sunita in characterizing the spatial and orientation dependence of effective interactions between clusters of LCS elements and replication origins (see Yompakdee & Huberman, 2004). In addition, Anita is collaborating with the laboratory of Bill Burhans to test the effects of mutations in candidate genes on chronological aging in budding yeast.

Sunita Ramanathan, PhD
Postdoctoral Trainee
Department of Cancer Genetics
Roswell Park Cancer Institute
Buffalo, New York 14263
716-845-1372 Office phone
716-845-8126 FAX
e-mail address not yet available

Sunita has identified five candidate proteins that preferentially bind to clusters of wild-type (but not mutant) LCS elements. She is currently constructing deletions of the genes encoding these five proteins so that she can test the effects of the gene deletions on replication timing. In addition, she is collaborating with the laboratory of Janet Leatherwood to characterize the replication times of every portion of the fission yeast genome.


Dr. Christine Brun
Assistant Professor of Bioinformatics
Laboratoire de Génétique et Physiologie du Développement
UMR6545 CNRS, Case 907
Parc Scientifique et Technologique de Luminy
13288 Marseille, Cedex 9, France
Tel 33 4 91 26 93 22
FAX 33 4 91 82 06 82
brun@lgpd.univ-mrs.fr
kris@fnac.net

Dr. Deborah Carlson
Department of Pediatrics, ICU
UT Southwestern
5323 Harry Hines Blvd
Dallas, TX 75390-9063
Deborah.Carlson@UTSouthwestern.edu

Dr. Dharani Dhar Dubey
Chair, Department of Biotechnology
VBS Purvanchal University
Jaunpur - 221001
INDIA
dharanidhar1@sify.com

Temesgen Fufa, B.S., M.S.
tfa32@yahoo.com

Temesgen received his Master's degree from our laboratory in 2003. He is now living in Sweden.

Soo-Mi Kim, Ph.D.
210 S. Mentor Ave #11
Pasadena, CA 91106
soomikim65@hanmail.net.

Deborah Mahoney, Ph.D.
c/o Dr. Paul D. Soloway
Division of Nutritional Sciences
Cornell University
108 Savage Hall
Ithaca, NY 14853
pds28@cornell.edu

Maria Marchetti, Ph.D.
Research Assistant Professor
Florida Atlantic University
Charles E. Schmidt College of Science
777 Glades Road, P.O. Box 3091
Boca Raton, FL 33431
mmarche@fau.edu

Dr. Kevin Nawotka
Senior Scientist Xenogen
860 Atlantic Avenue
Alameda, CA 94501
knawotka@xenogen.com

Dr. J. Aquiles Sanchez
Research Associate Department of Biology, Bassine 235
Brandeis University
415 South Street
Waltham, MA 02254-9110
617-736-3111 Office phone
617-736-3107 FAX
sanchez@binah.cc.brandeis.edu

Donna Scott, B.A.
Former technician (retired in 2005)
laughalot823@yahoo.com

Karuna Sharma, Ph.D.
University at Buffalo
State University of New York
School of Dental Medicine
116 Foster Hall
Buffalo, NY 14214
e-mail address not yet available

Dr. Ivan T. Todorov
City of Hope Medical Center
Department of Diabetes, Endocrinology and Metabolism
Gonda 2009
1500 East Duarte Rd
Duarte, CA 91010
tel: 626-359-8111, ext. 65538
fax: 626-301-8136
email: itodorov@coh.org

Martin Weinberger, Ph.D.
Research Affiliate II (Burhans laboratory)
Department of Cellular Stress Biology
Roswell Park Cancer Institute
Buffalo, New York 14263
716-845-8436 Office phone
716-845-1698 FAX
martin.weinberger@roswellpark.org

Dr. Chulee Yompakdee
Department of Microbiology
Faculty of Science
Chulalongkorn University
Phyathai Rd., Patumwan
Bangkok 10330
Thailand
chulee@sc.chula.ac.th

Dr. Yeup Yoon
341 Mogam Biotechnology Research Institute
Po-jung Ri, Koosung-Myun, Yongin City, Kyunggi-do
Korea 449-910
yy@mogam.re.kr

Dongyi Zhang, Ph.D.
Division of Developmental Biology
Children's Hospital Research Foundation
3333 Burnet Avenue
Cincinnati, OH 45229
zhand0@chmcc.org

Jiguang Zhu, Ph.D., M.D.
Assistant Professor
New England Medical Center
Tufts University Medical School
Neurology Dept.
750 Washington Street
Boston, MA 02111
jzhu@massmed.org
jzhu99@hotmail.com


This page was updated on March 27, 2006.

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